Which organ is primarily responsible for detoxification in the body?

The liver is the primary organ responsible for detoxification in the body. It plays a crucial role in metabolizing various substances, including drugs, alcohol, and toxins. The liver converts these substances into less harmful forms that can be eliminated from the body.

This organ has specialized cells known as hepatocytes that carry out a variety of biochemical processes, including the breakdown of nutrients and the filtering of blood. The liver also produces bile, which aids in the digestion and absorption of fats and fat-soluble vitamins. Additionally, it stores essential nutrients and plays a role in regulating metabolism.

While the kidneys also contribute to detoxification by filtering waste products from the blood and excreting them through urine, their primary function is more about maintaining fluid and electrolyte balance rather than the comprehensive detoxification processes performed by the liver. The lungs are mainly involved in gas exchange, and the spleen plays a role in blood filtration and immune response but does not have a primary detoxification function. Thus, the liver's multifaceted role in detoxification makes it the correct choice.